This month Remember, Remember…

You Must Remember This

With great interest, I have been observing the developments in continuous lifelong capture, which has been gaining momentum over the last few years. By lifelong capture, I refer to someone digitally logging every moment and element of their lives, a usually permanent recording of an activity by a participant in the activity. This process often results in the unanticipated capture of valuable mo...

T-cell memory: You must remember this…

While antigen-inexperienced (naive) T cells appear to require constant tickling of their receptor by self-antigens for homeostasis, antigen-experienced (memory) T cells have no such requirement. An implication is that long-term T-cell memory does not depend on persisting antigen.

Health reform: remember why we got into this.

Remember kerion celsi.

To cite: Brissos J, Gouveia C, Neves C, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2013-200594 DESCRIPTION A healthy 3-year-old boy presented to our emergency department with a 2-week history of inflammatory scalp lesions. Physical examination revealed diffuse erythematous lesions, with focal areas of alopecia and several pustular patches with extensi...

Acid to remember

Antibodies against a vaccine vector render T cells more susceptible to HIV-1 infection, say Perreau et al. on page 2717. Their results may help explain the failure of a recent HIV vaccine trial. The HIV-1 vaccine used in Merck's STEP trial relied on a weakened form of a common cold virus, Adenovirus 5 (Ad5), to carry bits of HIV into the body. One worry about the Ad5 vector was that widespread ...